<i>tcrB</i>, a Gene Conferring Transferable Copper Resistance in<i>Enterococcus faecium</i>: Occurrence, Transferability, and Linkage to Macrolide and Glycopeptide Resistance

Abstract excerpt

A newly discovered gene, designated tcrB, which is located on a conjugative plasmid conferring acquired copper resistance in Enterococcus faecium, was identified in an isolate from a pig. The tcrB gene encodes a putative protein belonging to the CPx-type ATPase family with homology (46%) to the CopB protein from Enterococcus hirae. The tcrB gene was found in E. faecium isolated from pigs (75%), broilers (34%),...

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