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Article

Exploring prokaryotic diversity in the genomic era.

Genome biology - 1 Jan 2002

Hugenholtz Philip

Abstract excerpt

Our understanding of prokaryote biology from study of pure cultures and genome sequencing has been limited by a pronounced sampling bias towards four bacterial phyla - Proteobacteria, Firmicutes, Actinobacteria and Bacteroidetes - out of 35 bacterial and 18 archaeal phylum-level lineages. This bias is beginning to be rectified by the use of phylogenetically directed isolation strategies and by directly accessing...

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Identifiers

PMID: 11864374
DOI: 10.1186/gb-2002-3-2-reviews0003
PMCID: PMC139013

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