Molecular characterization and chromosome assignment of the porcine gene COX7A1 coding for the muscle specific cytochrome c oxidase subunit VIIa-M.

doi:10.1159/000048814

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Article

Molecular characterization and chromosome assignment of the porcine gene COX7A1 coding for the muscle specific cytochrome c oxidase subunit VIIa-M.

Cytogenetics and cell genetics - 1 Jan 2001

Drögemüller C, Kuiper H, Voss-Nemitz R, Brenig B, Distl O, Leeb T

Abstract excerpt

The COX7A1 gene encodes a heart- and muscle-specific isoform of the subunit VIIA of cytochrome c oxidase, which is the last component of the mitochondrial electron transfer chain. Cloning and characterization of the porcine COX7A1 gene revealed a highly conserved organization with respect to other mammalian COX7A1 orthologs. The porcine gene consists of four exons spanning approximately 1.5 kb and codes for a...

Topics

Animals
Chromosomes
Electron Transport Complex IV
Exons
In Situ Hybridization, Fluorescence
Isoenzymes
Muscles
Mutation
Physical Chromosome Mapping
Protein Subunits
Radiation Hybrid Mapping
Swine

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Open in PubMed

Identifiers

PMID: 11856879
DOI: 10.1159/000048814

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