Article
Low-density lipoprotein receptor gene mutation analysis and clinical correlation in Belgian hypercholesterolaemics.
Molecular and cellular probes - 1 Dec 2001
Van Gaal L F, Peeters A V, De Block C E, de Leeuw I H, Thiart R, Kotze M J
Abstract excerpt
It is generally believed that patients with familial hypercholesterolaemia (FH) have a higher cardiovascular risk than hypercholesterolaemics without a defect in the low-density lipoprotein receptor (LDLR) gene. However, no conclusive evidence to support this view has yet been presented. We investigated this aspect in Belgian hyperlipidaemics as part of a comprehensive effort to determine the impact of FH in this...
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