Measure of molecular diversity within the Trypanosoma brucei subspecies Trypanosoma brucei brucei and Trypanosoma brucei gambiense as revealed by genotypic characterization.

doi:10.1006/expr.2001.4666

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Article

Measure of molecular diversity within the Trypanosoma brucei subspecies Trypanosoma brucei brucei and Trypanosoma brucei gambiense as revealed by genotypic characterization.

Experimental parasitology - 1 Nov 2001

Agbo E C, Majiwa P A, Claassen E J, Roos M H

Abstract excerpt

We have evaluated whether sequence polymorphisms in the rRNA intergenic spacer region can be used to study the relatedness of two subspecies of Trypanosoma brucei. Thirteen T. brucei isolates made up of 6 T. b. brucei and 7 T. b. gambiense were analyzed using restriction fragment length polymorphism (RFLP). By PCR-based restriction mapping of the ITS1-5.8S-ITS2 ribosomal repeat unit, we found a fingerprint...

Topics

Animals
Base Sequence
Cluster Analysis
Consensus Sequence
DNA, Protozoan
DNA, Ribosomal
Genetic Variation
Genotype
Humans
Molecular Sequence Data
Phylogeny
Polymerase Chain Reaction
Polymorphism, Restriction Fragment Length

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

RNA, Ribosomal, 5.8S

Repetitive Sequences, Nucleic Acid

Sequence Alignment

Species Specificity

Trypanosoma brucei brucei

Source

Open in PubMed

Identifiers

PMID: 11846522
DOI: 10.1006/expr.2001.4666

Provenance

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