Article
Large offspring syndrome and other consequences of ruminant embryo culture<i>in vitro</i>: Relevance to blastocyst culture in human ART
1 Jan 2000
Abstract excerpt
In vitro production of embryos from domestic animals is used to augment conventional genetic improvement programmes in agriculture and to facilitate advances in gene transfer and cloning. However, production of embryos in vitro exposes them to hazards not normally encountered in vivo and, as a result, there have been unforeseen consequences including the large offspring syndrome. This syndrome is manifest as...
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