Resistance to Antiretroviral Treatment in Gabon: Need for Implementation of Guidelines on Antiretroviral Therapy Use and HIV-1 Drug Resistance Monitoring in Developing Countries

Abstract excerpt

The protease and reverse transcriptase (RT) genes were studied in antiretroviral (ARV)-experienced and drug-naive HIV-1-infected individuals in Libreville, Gabon. We have shown, although on a limited number of samples that in 58% (11/19) of the patients, with a mean of 17.7 months of ARV drug experience, major mutations inevitably inducing resistances to ARV drugs were present. Resistance was mainly observed to...

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