Article
Choroid plexus carcinomas and rhabdoid tumors: phenotypic and genotypic overlap.
Pediatric and developmental pathology : the official journal of the Society for Pediatric Pathology and the Paediatric Pathology Society - 1 Jan 2000
Wyatt-Ashmead J, Kleinschmidt-DeMasters B, Mierau G W, Malkin D, Orsini E, McGavran L, Foreman N K
Abstract excerpt
Five of six poorly differentiated choroid plexus carcinomas identified at our institution contained cells displaying a rhabdoid phenotype. Immunoperoxidase stains showed focal positivity for cytokeratin, epithelial membrane antigen, glial fibrillary acidic protein, S100, and vimentin. The MIB-1 proliferative index ranged from 7.0% to 27.1%. All six tumors were p53 positive. Only the one child with Li-Fraumeni...
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