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Article

Mutational analysis of StAR gene in adrenal tumors.

International journal of cancer - 20 Jan 2002

Stigliano Antonio, Caiola Stefania, Siniscalchi Ester, Papini Enrico, Crescenzi Anna, Monti Salvatore, Arnaldi Giorgio, Mantero Franco, Sciarra Francesco, Toscano Vincenzo

Abstract excerpt

Adrenal adenomas and carcinomas are mostly monoclonal, suggesting that a genetic alteration in a progenitor cell may contribute to their development. However, the molecular pathogenesis of these tumors still remains unclear. It has been already excluded that activating mutations of the ACTH receptor or of G protein stimulator alpha sub-units, affecting cAMP pathway, is involved in the tumorigenesis. Therefore,...

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Identifiers

PMID: 11774288
DOI: 10.1002/ijc.1604

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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