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Article

Countrywide spread of CTX-M-3 extended-spectrum beta-lactamase-producing microorganisms of the family Enterobacteriaceae in Poland.

Antimicrobial agents and chemotherapy - 1 Jan 2002

Baraniak Anna, Fiett Janusz, Sulikowska Agnieszka, Hryniewicz Waleria, Gniadkowski Marek

Abstract excerpt

Eighty-four clinical isolates of the family Enterobacteriaceae, recovered from 1998 to 2000 in 15 hospitals in 10 Polish cities, were analyzed. All the isolates produced beta-lactamases with pIs of 8.4 and 5.4, and the pI 8.4 enzymes were demonstrated to hydrolyze cefotaxime but not ceftazidime in the in vitro bioassay. PCR analysis and DNA sequencing have revealed that in all cases the pI 8.4 beta-lactamase was...

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Identifiers

PMID: 11751126
DOI: 10.1128/AAC.46.1.151-159.2002
PMCID: PMC126981

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