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Article

Functional cloning and characterization of a plant efflux carrier for multidrug and heavy metal detoxification.

The Journal of biological chemistry - 15 Feb 2002

Li Legong, He Zengyong, Pandey Girdhar K, Tsuchiya Tomofusa, Luan Sheng

Abstract excerpt

We have identified a detoxifying efflux carrier from Arabidopsis using a functional cloning strategy. A bacterial mutant, KAM3, is deficient in multidrug resistance and does not survive on medium containing norfloxacin. After transformation of KAM3 cells with an Arabidopsis cDNA library, transformants were selected for restored growth on the toxic medium. One cDNA clone that complemented KAM3 encodes a novel...

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PMID: 11739388
DOI: 10.1074/jbc.M108777200

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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