Article
Molecular cloning and disruption of a novel gene encoding UDP-glucose: tetrahydrobiopterin alpha-glucosyltransferase in the cyanobacterium Synechococcus sp. PCC 7942.
FEBS letters - 3 Aug 2001
Choi Y K, Hwang Y K, Park Y S
Abstract excerpt
The gene encoding UDP-glucose:tetrahydrobiopterin alpha-glucosyltransferase (BGluT) was cloned from the genomic DNA of Synechococcus sp. PCC 7942. The encoded protein consisting of 359 amino acid residues was verified in vitro and in vivo to be responsible for the synthesis of tetrahydrobiopterin (BH4)-glucoside produced in the organism. The BGluT gene is the first cloned in pteridine glycosyltransferases and...
Topics
- Aclarubicin
- Amino Acid Sequence
- Antineoplastic Combined Chemotherapy Protocols
- Bacterial Proteins
- Base Sequence
- Biopterins
- Blotting, Southern
- Blotting, Western
- Cell Division
- Chromatography, High Pressure Liquid
- Cloning, Molecular
- Cyanobacteria
- Cytarabine