Genomic analysis of the erythromycin resistance element Tn5398 from Clostridium difficile The GenBank accession number for the Tn5398 element and flanking sequence is AF109075.

Abstract excerpt

Clostridium difficile is a nosocomial pathogen that causes a range of chronic intestinal diseases, usually as a result of antimicrobial therapy. Macrolide-lincosamide-streptogramin B (MLS) resistance in C. difficile is encoded by the Erm B resistance determinant, which is thought to be located on a conjugative transposon, Tn5398. The 9630 bp Tn5398 element has been cloned and completely sequenced and its...

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