Article
Dietary conjugated linoleic acid modulates phenotype and effector functions of porcine CD8(+) lymphocytes.
The Journal of nutrition - 1 Sept 2001
Bassaganya-Riera J, Hontecillas R, Zimmerman D R, Wannemuehler M J
Abstract excerpt
In vivo vaccination and challenge studies have demonstrated that CD8(+) lymphocytes are essential for the development of cell-mediated protection against intracellular pathogens and neoplastic cells. Depletion of peripheral blood CD8(+) cells interferes with clearance of viruses and intracellular fungi, induction of delayed type hypersensitivity responses and antitumoral activity. In contrast to humans or mice,...
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