Biofilm Formation by the Fungal Pathogen <i>Candida albicans</i> : Development, Architecture, and Drug Resistance

Abstract excerpt

Biofilms are a protected niche for microorganisms, where they are safe from antibiotic treatment and can create a source of persistent infection. Using two clinically relevant Candida albicans biofilm models formed on bioprosthetic materials, we demonstrated that biofilm formation proceeds through three distinct developmental phases. These growth phases transform adherent blastospores to well-defined cellular...

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