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Article

The molecular basis of inherited afibrinogenaemia.

Thrombosis and haemostasis - 1 Jul 2001

Neerman-Arbez M

Abstract excerpt

This article reviews the substantial progress made in understanding the molecular basis of inherited afibrinogenaemia (or congenital afibrinogenaemia), an autosomal recessive disorder characterised by the complete absence of detectable fibrinogen. The identification in 1999 of the first genetic defect, recurrent homozygous deletions of approximately 11 kb of the fibrinogen alpha-chain (FGA) gene, revealed that...

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PMID: 11487003

Genes

FGA

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