Article
Demonstration of reinfection and reactivation in HIV-negative autopsied cases of secondary tuberculosis: multilesional genotyping of Mycobacterium tuberculosis utilizing IS 6110 and other repetitive element-based DNA fingerprinting.
Tuberculosis (Edinburgh, Scotland) - 1 Jan 2001
du Plessis D G, Warren R, Richardson M, Joubert J J, van Helden P D
Abstract excerpt
SETTING: Secondary tuberculosis may follow reinfection or endogenous reactivation. The design of effective preventive and treatment protocols requires knowledge about the relative importance of these mechanisms in specific communities. Molecular typing of Mycobacterium tuberculosis has permitted linkage of cases and demonstration of patterns of inter- or intrapatient strain diversity correlating with reinfection...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.