Article
Superficial fibromatoses are genetically distinct from deep fibromatoses.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc - 1 Jul 2001
Montgomery E, Lee J H, Abraham S C, Wu T T
Abstract excerpt
Whereas deep fibromatoses (abdominal, extra-abdominal, mesenteric) display locally aggressive behavior, superficial fibromatoses typically remain small and less likely to recur despite essentially identical morphology. Somatic beta-catenin or APC gene mutations have been reported in < or =74% of sporadic deep fibromatoses and in virtually 100% of Gardner syndrome-associated fibromatoses, whereas genetic events in...
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