Article
Role of Enterococcus faecalis surface protein Esp in the pathogenesis of ascending urinary tract infection.
Infection and immunity - 1 Jul 2001
Shankar N, Lockatell C V, Baghdayan A S, Drachenberg C, Gilmore M S, Johnson D E
Abstract excerpt
Enterococcus faecalis bacteria isolated from patients with bacteremia, endocarditis, and urinary tract infections more frequently express the surface protein Esp than do fecal isolates. To assess the role of Esp in colonization and persistence of E. faecalis in an animal model of ascending urinary tract infection, we compared an Esp(+) strain of E. faecalis to its isogenic Esp-deficient mutant. Groups of CBA/J...
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