Article
Alexander disease: new insights from genetics.
Journal of neuropathology and experimental neurology - 1 Jun 2001
Messing A, Goldman J E, Johnson A B, Brenner M
Abstract excerpt
Prior to finding that GFAP mutations underlie many cases of Alexander disease, it was unclear whether the disease originated in astrocytes or if the formation of Rosenthal fibers was a response to an external insult. It was also unclear whether the etiology of the disease was environmental or genetic. For many cases of Alexander disease, these questions have now been answered. An immediate clinical benefit of...
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