Article
Current concepts on the genetics of asthma.
Current opinion in pediatrics - 1 Jun 2001
Hakonarson H, Wjst M
Abstract excerpt
Asthma is a complex genetic disorder with variable phenotype, largely attributed to the interactions of the environment and multiple genes, each potentially having small effects. Numerous asthma and atopy loci have been reported in studies demonstrating associations and/or linkage of the asthma-associated phenotypes, atopy, elevated IgE levels, and bronchial hyperresponsiveness to alleles of microsatellite...
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