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Article

The GM2 gangliosidoses databases: allelic variation at the HEXA, HEXB, and GM2A gene loci.

Genetics in medicine : official journal of the American College of Medical Genetics - 1 Jan 2000

Cordeiro P, Hechtman P, Kaplan F

Abstract excerpt

The GM2 gangliosidoses are a group of recessive disorders characterized by accumulation of GM2 ganglioside in neuronal cells. The genes responsible for these disorders are HEXA (Tay-Sachs disease and variants), HEXB (Sandhoff disease and variants), and GM2A (AB variant of GM2 gangliosidosis). We report the establishment of three relational locus-specific databases recording allelic variation at the HEXA, HEXB,...

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Identifiers

PMID: 11339652
DOI: 10.1097/00125817-200011000-00003

Genes

HEXA
HEXB

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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