Article
Yesterday's polyploids and the mystery of diploidization.
Nature reviews. Genetics - 1 May 2001
Wolfe K H
Abstract excerpt
Thirty years after Susumu Ohno proposed that vertebrate genomes are degenerate polyploids, the extent to which genome duplication contributed to the evolution of the vertebrate genome, if at all, is still uncertain. Sequence-level studies on model organisms whose genomes show clearer evidence of ancient polyploidy are invaluable because they indicate what the evolutionary products of genome duplication can look...
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