Symposium on the etiology of hypertension--summarizing studies in 20th century. 1. Hypertension and genes.

Abstract excerpt

Under classical strategy, scientists have tried first to find a physiological phenomenon specific for essential hypertension, then to identify the protein underlying the physiological abnormality, and finally to clarify the causative gene which encoded the protein. On the other hand, under the reverse genetic approach, the correlation between hypertension and genetic abnormality is identified first, and then the...

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