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Article

Major histocompatibility complex (MHC) variation in the endangered Mexican wolf and related canids.

Heredity - 1 Dec 2000

Hedrick P W, Lee R N, Parker K M

Abstract excerpt

We have examined in Mexican wolves and related canids the amount of genetic variation for a class II gene in the major histocompatibility complex (MHC), thought to be part of the most important genetic basis for pathogen resistance in vertebrates. In Mexican wolves, descended from only seven founders over three lineages, there were five different alleles. These were in three phylogenetic groups, only one of which...

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PMID: 11240629
DOI: 10.1046/j.1365-2540.2000.00805.x

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