Article
Genetic determinants of type 2 diabetes.
Recent progress in hormone research - 1 Jan 2001
Froguel P, Velho G
Abstract excerpt
Hyperglycemia of type 2 diabetes mellitus (T2DM) results from a complex interplay of genetic and environmental factors that influence a number of intermediate traits (e.g., beta-cell mass, insulin secretion, insulin action, fat distribution, obesity). The primary biochemical events leading to diabetes are still unknown in most cases. Although several monogenic forms of diabetes have been identified, T2DM seems to...
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