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Article

The tuberous sclerosis-1 (TSC1) gene product hamartin suppresses cell growth and augments the expression of the TSC2 product tuberin by inhibiting its ubiquitination

14 Dec 2000

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 11175345
DOI: 10.1038/sj.onc.1204009

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Related research

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The tuberous sclerosis-1 (TSC1) gene product hamartin suppresses cell growth and augments the expression of the TSC2 product tuberin by inhibiting its ubiquitinationPMID 11175345Read ↗

The tuberous sclerosis gene products hamartin and tuberin are multifunctional proteins with a wide spectrum of interacting partnersSemantic proximity Read ↗

Tuberous sclerosis complex, implication from a rare genetic disease to common cancer treatmentSemantic proximity Read ↗

New insights into tuberous sclerosis complex: from structure to pathogenesisSemantic proximity Read ↗

TSC1 and TSC2: genes that are mutated in the human genetic disorder tuberous sclerosis.Semantic proximity Read ↗

Hamartin, the tuberous sclerosis complex 1 gene product, interacts with polo-like kinase 1 in a phosphorylation-dependent manner.Semantic proximity Read ↗

The TSC1 gene product, hamartin, negatively regulates cell proliferationSemantic proximity Read ↗

Genetics and Molecular Biology of Tuberous Sclerosis ComplexSemantic proximity Read ↗

Tumour suppressors hamartin and tuberin: intracellular signalling.Semantic proximity Read ↗

Therapeutic Approaches to Tuberous Sclerosis Complex: From Available Therapies to Promising Drug TargetsSemantic proximity Read ↗

Molecular genetic basis of tuberous sclerosis complex: from bench to bedside.Semantic proximity Read ↗

Tuberin and hamartin are aberrantly expressed and linked to clinical outcome in human breast cancer: The role of promoter methylation of TSC genesSemantic proximity Read ↗

Proteins interacting with the tuberous sclerosis gene products.Semantic proximity Read ↗

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