Article
Linkage of the dopamine D4 receptor gene and attention-deficit/hyperactivity disorder.
Journal of the American Academy of Child and Adolescent Psychiatry - 1 Dec 2000
Sunohara G A, Roberts W, Malone M, Schachar R J, Tannock R, Basile V S, Wigal T, Wigal S B, Schuck S, Moriarty J, Swanson J M, Kennedy J L, Barr C L
Abstract excerpt
OBJECTIVE: There is considerable evidence supporting a genetic component in the etiology of attention-deficit/hyperactivity disorder (ADHD). Because stimulant medications act primarily on the dopaminergic system, dopamine system genes are prime candidates for genetic susceptibility factors for ADHD. Previous studies by several groups have observed a significant association of ADHD and an allele with 7 copies of...
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