The Use of Fluorescence In Situ Hybridization (FISH) on Paraffin-Embedded Tissue Sections for the Study of Microchimerism

Abstract excerpt

We describe here a simple and versatile method of fluorescence in situ hybridization (FISH) on paraffin-embedded tissue sections with specific application in the study of microchimerism, that is, the presence of intact foreign cells within an individual. This is accomplished through the use of X and Y chromosome-specific probes to identify the presence of male nuclei within a tissue section from a female, and...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Assisted Reproductive Technology and Twin Pregnancy
• Share to Prenatal Screening and Diagnostics
• Share to Reproductive System and Pregnancy