Article
Pathogenesis of diabetes-induced congenital malformations.
Upsala journal of medical sciences - 1 Jan 2000
Eriksson U J, Borg L A, Cederberg J, Nordstrand H, Simán C M, Wentzel C, Wentzel P
Abstract excerpt
The increased rate of fetal malformation in diabetic pregnancy represents both a clinical problem and a research challenge. In recent years, experimental and clinical studies have given insight into the teratological mechanisms and generated suggestions for improved future treatment regimens. The teratological role of disturbances in the metabolism of inositol, prostaglandins, and reactive oxygen species has been...
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