Article
Vitamin D receptor polymorphisms and nutritional rickets in Nigerian children.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research - 1 Nov 2000
Fischer P R, Thacher T D, Pettifor J M, Jorde L B, Eccleshall T R, Feldman D
Abstract excerpt
Nutritional rickets is common in Nigeria where vitamin D deficiency is rare and dietary insufficiency of calcium is common. It occurs more commonly in siblings of affected children than of unaffected children. Postulating that vitamin D receptor (VDR) polymorphisms might relate to the susceptibility of some Nigerian children to develop rickets in the setting of low calcium intake, we compared the VDR genotypes,...
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