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Article

A Tumultuous Year for Gene Therapy

1 Nov 2000

Abstract excerpt

On September 17, 1999, 18-year-old Jesse Gelsinger died at the University of Pennsylvania following administration of recombinant adenoviral vector containing the orinithine transcarbamylase (OTC) gene. In the decade-old history of nearly 400 clinical gene therapy trials involving well over 4000 patients, Gelsinger's was and still remains the only death directly attributable to gene delivery vehicle. Why, then,...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 11082313
DOI: 10.1006/mthe.2000.0213

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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