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Article

Developmental expression of myotonic dystrophy protein kinase in brain and its relevance to clinical phenotype.

Acta neuropathologica - 1 Nov 2000

Endo A, Motonaga K, Arahata K, Harada K, Yamada T, Takashima S

Abstract excerpt

To investigate the pathophysiologic role of myotonic dystrophy protein kinase (DMPK) in the brain in myotonic dystrophy (MD), the developmental characteristics of DMPK immunoreactivity in the central nervous system and its alteration with disease were studied. Eleven patients' brain with MD (5 congenital form, 6 adult form) were examined by immunohistochemistry using a specific antibody against synthetic DMPK...

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Identifiers

PMID: 11045673
DOI: 10.1007/s004010000216

Genes

DMPK

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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