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Article

Enteroviruses Can Persist with or without Active Viral Replication in Cardiac Tissue of Patients with End‐Stage Ischemic or Dilated Cardiomyopathy

1 Oct 2000

Abstract excerpt

To investigate enterovirus replication versus persistence in end-stage cardiac diseases, endomyocardial biopsies from explanted hearts of 70 patients with idiopathic dilated cardiomyopathy (IDCM), 64 patients with chronic coronary disease (CCD), and 45 donors of healthy hearts (controls) were examined by reverse transcriptase-polymerase chain reaction for genomic and antigenomic enterovirus RNA and by VP1 antigen...

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PMID: 10979922
DOI: 10.1086/315818

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