Cloning genes whose levels of expression are altered by metals: implications for human health research.

Abstract excerpt

When cells are exposed to toxicants, changes in gene expression ensue. To date, there is little information on gene expression changes induced by metals in mammalian cells. The basic methods for identifying altered gene expression of both a temporary and a permanent nature are outlined, with examples drawn mostly from what is known about metal-induced changes in gene expression. The application of this...

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