Article
Genetic basis of acanthosis nigricans in Mexican Americans and its association with phenotypes related to type 2 diabetes.
Human genetics - 1 May 2000
Burke J P, Duggirala R, Hale D E, Blangero J, Stern M P
Abstract excerpt
Acanthosis nigricans (AN) is a skin condition associated with hyperinsulinemia and insulin resistance and has been shown to be a risk factor for type 2 diabetes. The influence of genetic factors on AN and the basis of its association with type 2 diabetes and its risk factors are unknown. Using data from 397 participants from two Mexican American family studies, we investigated the heritability of AN and its...
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