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Identification of a novel HLA-B46 allele, B*4602, in Japanese.

Tissue antigens - 1 May 2000

Akesaka T, Kashiwase K, Shimamura M, Ishikawa Y, Tanaka H, Fujii M, Akaza T, Hando K, Yuasa S, Takahashi T, Juji T

Abstract excerpt

The B*4602 was identified in a healthy Japanese donor. The B46 variant antigen differed serologically from B46. The nucleotide sequence of B*4602 differed from that of B*4601 by a single base (from A to G) at position 293 in exon 2. The substitution changed the amino acid Asp at position 74 to Gly. The gene frequency of B*4602 in the Japanese population is extremely low. The presumed haplotype of B*4602 was...

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Identifiers

PMID: 10885569
DOI: 10.1034/j.1399-0039.2000.550511.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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