Article
Maturation phenotype of Sertoli cells in testicular biopsies of azoospermic men.
Human reproduction (Oxford, England) - 1 Jul 2000
Bar-Shira Maymon B, Paz G, Elliott D J, Hammel I, Kleiman S E, Yogev L, Hauser R, Botchan A, Yavetz H
Abstract excerpt
The involvement of Sertoli cells in different spermatogenic impairments has been studied by an immunohistomorphometric technique using cytokeratin-18 (CK-18) as a marker for immature Sertoli cells. CK-18 is known to be expressed in Sertoli cells during prenatal and prepubertal differentiation and is normally lost at puberty. Forty-nine azoospermic men were included in the current study. Quantitative measurements...
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