Insulin-Like Growth Factor Receptors and Their Ligands in Gonads of a Hermaphroditic Species, the Gilthead Seabream (Sparus aurata): Expression and Cellular Localization1

Abstract excerpt

Expression of insulin-like growth factor (IGF)-I, IGF-II, and IGF type I receptor (IGF-1R) genes was studied in gonads at different developmental stages of the protandrous hermaphroditic species the gilthead seabream (Sparus aurata) by reverse transcription-polymerase chain reaction and Northern blot analysis. Both IGF-I and IGF-II mRNA levels were highest in bisexual gonads and decreased during gonadal...

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