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Article

Molecular basis of gynecological cancer.

Annals of the New York Academy of Sciences - 1 Jan 2000

Spandidos D A, Dokianakis D N, Kallergi G, Aggelakis E

Abstract excerpt

Alterations in the cellular genome affecting the expression or function of genes controlling cell growth and differentiation are considered to be the main cause of cancer. Genes that cause cancer are of two distinct types: oncogenes and onco-suppressor genes. The normal proto-oncogene can be converted into an active oncogene by deletion or point mutation in its coding sequence, gene amplification, and by specific...

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Source

Identifiers

PMID: 10818392
DOI: 10.1111/j.1749-6632.2000.tb06216.x

Genes

BRCA1
DCC
PTEN

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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