Article
The properties of hNT cells following transplantation into the subventricular zone of the neonatal forebrain.
Experimental neurology - 1 May 2000
Zigova T, Pencea V, Sanberg P R, Luskin M B
Abstract excerpt
Neurons derived from the human teratocarcinoma cell line (hNT) establish structural polarity and a fully mature phenotype following transplantation into the rodent brain. Here we describe the transplantation of hNT cells into the anterior part of neonatal subventricular zone (SVZa), which is a prolific region of neuronal progenitor cells. Ordinarily, the progeny of endogenous or homotopically transplanted SVZa...
Topics
- Animals
- Animals, Newborn
- Cell Differentiation
- Cell Line
- Cell Movement
- Cell Survival
- Cell Transplantation
- Fluorescent Dyes
- Graft Survival
- Humans
- Neurons
- Olfactory Bulb
- Organic Chemicals
- Phenotype
- Prosencephalon
- Rats
