Article
Vitamin-D receptor genotype and renal disorder in Japanese patients with systemic lupus erythematosus.
Nephron - 1 May 2000
Ozaki Y, Nomura S, Nagahama M, Yoshimura C, Kagawa H, Fukuhara S
Abstract excerpt
BACKGROUND/AIMS: It is known that allelic variants of the gene encoding the vitamin-D receptor (VDR) detected by BsmI increase the risk of some advanced malignant tumors, suggesting that such variants may cause functional differences in 1,25(OH)(2) vitamin D(3). We examined the VDR genes of Japanese systemic lupus erythematosus (SLE) patients, to determine whether different genotypes are correlated with SLE or...
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