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Article

Neutral evolution of the sex-determining gene transformer in Drosophila.

Genetics - 1 Apr 2000

McAllister B F, McVean G A

Abstract excerpt

The amino acid sequence of the transformer (tra) gene exhibits an extremely rapid rate of evolution among Drosophila species, although the gene performs a critical step in sex determination. These changes in amino acid sequence are the result of either natural selection or neutral evolution. To differentiate between selective and neutral causes of this evolutionary change, analyses of both intraspecific and...

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Identifiers

PMID: 10747064
DOI: 10.1093/genetics/154.4.1711
PMCID: PMC1461033

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