Article
A brief history of Drosophila's contributions to genome research.
Science (New York, N.Y.) - 24 Mar 2000
Rubin G M, Lewis E B
Abstract excerpt
The sequence of the Drosophila melanogaster genome presented in this issue of Science is the latest milestone in nine decades of research on this organism. Genetic and physical mapping, whole-genome mutational screens, and functional alteration of the genome by gene transfer were pioneered in metazoans with the use of this small fruit fly. Here we look at some of the instances in which work on Drosophila has led...
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