Article
The myotonic dystrophies.
Seminars in neurology - 1 Jan 1999
Thornton C
Abstract excerpt
Myotonic dystrophy, or dystrophia myotonica (DM), is the most common inherited muscle disorder in adults. DM is a multisystem disease in which the most disabling feature is muscle wasting that begins in the distal limb and cranial muscles. The genetic basis for DM is an expanded CTG repeat in the DMPK gene on chromosome 19. The size of the expanded repeat, and the severity of the disease, tend to increase in...
Topics
- Anticipation, Genetic
- Cataract
- Genetic Testing
- Heart Block
- Humans
- Insulin Resistance
- Muscles
- Mutation
- Myotonic Dystrophy
- Trinucleotide Repeats