Article
Correlates of sleep and waking in Drosophila melanogaster.
Science (New York, N.Y.) - 10 Mar 2000
Shaw P J, Cirelli C, Greenspan R J, Tononi G
Abstract excerpt
Drosophila exhibits a circadian rest-activity cycle, but it is not known whether fly rest constitutes sleep or is mere inactivity. It is shown here that, like mammalian sleep, rest in Drosophila is characterized by an increased arousal threshold and is homeostatically regulated independently of the circadian clock. As in mammals, rest is abundant in young flies, is reduced in older flies, and is modulated by...
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