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Article

Specificity mutants of the binding protein of the oligopeptide transport system of Lactococcus lactis.

Journal of bacteriology - 1 Mar 2000

Picon A, Kunji E R, Lanfermeijer F C, Konings W N, Poolman B

Abstract excerpt

The kinetic properties of wild-type and mutant oligopeptide binding proteins of Lactococcus lactis were determined. To observe the properties of the mutant proteins in vivo, the oppA gene was deleted from the chromosome of L. lactis to produce a strain that was totally defective in oligopeptide transport. Amplified expression of the oppA gene resulted in an 8- to 12-fold increase in OppA protein relative to the...

Topics

Amino Acid Sequence
Bacterial Proteins
Biological Transport
Bradykinin
Carrier Proteins
Fluorescence
Gene Deletion
Immunoblotting
Lactococcus lactis
Lipoproteins
Molecular Sequence Data

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Mutagenesis, Site-Directed

Mutation

Oligopeptides

Source

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Identifiers

PMID: 10692365
DOI: 10.1128/JB.182.6.1600-1608.2000
PMCID: PMC94457

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