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Article

Identification of a polymorphism in the promoter region of DRD4 associated with the human novelty seeking personality trait.

Molecular psychiatry - 1 Jan 2000

Okuyama Y, Ishiguro H, Nankai M, Shibuya H, Watanabe A, Arinami T

Abstract excerpt

Polymorphism in the human dopamine D4 receptor gene (DRD4) exon III has been associated in some but not all studies of the human personality trait of Novelty Seeking. We searched for polymorphisms in the 5' region of DRD4 and identified six polymorphisms as follows: -1217G Ins/Del, -809G/A, -616C/G, -603T Ins/Del, -602(G)8-9, and -521C/T. Associations between these polymorphisms and personality traits measured by...

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Share to Antisense Elements (Genetics)
Share to Dopamine

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Exploratory Behavior

Share to Linkage Disequilibrium

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Share to Polymorphism, Single-Stranded Conformational

Share to Receptors, Dopamine D2

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Source

Identifiers

PMID: 10673770
DOI: 10.1038/sj.mp.4000563

Genes

DRD4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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