Article
Genotypes of TT virus (TTV) compared between liver disease patients and healthy individuals using a new PCR system capable of differentiating 1a and 1b types from others*.
Archives of virology - 1 Jan 1999
Hijikata M, Iwata K, Ohta Y, Nakao K, Matsumoto M, Matsumoto H, Kanai K, Baba K, Samokhvalov E I, Mishiro S
Abstract excerpt
TT virus (TTV) lacks obvious pathogenicity; almost all of the infected hosts are symptom-free. A possibility remains, however, that certain strains can cause liver disease while most others are non-pathogenic. Genotypes 1 a and 1 b have been proposed to contain such pathogenic strains. To test this possibility, we constructed a PCR system capable of detecting TTV of the 1 a and 1 b genotypes differentially from...
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