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Quantitative analysis of gene amplification in insecticide-resistant Culex mosquitoes

15 Feb 2000

Abstract excerpt

The amplification of carboxylesterase structural genes followed by their overexpression is the most common mechanism of resistance to organophosphorus insecticides in Culex mosquitoes. Most resistant Culex quinquefasciatus mosquitoes have co-amplified estalpha2(1) and estbeta2(1) genes. Recently, Southern, DNA dot-blot analysis and phosphorimaging technology were used to quantify the est gene copy number in...

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PMID: 10657234
DOI: 10.1042/0264-6021:3460017

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Source receipt: pubmed, retrieved 7 Sept 2026.

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